Protein Partnering and Function

Build "partnerships" between a protein and small molecules and explore the effects of surface charge, polarity, and shape on partnering.

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Requirements

On OS X 10.9 or newer, you will need to install a launcher application to run this Java activity. If you have not already installed it, please:

  • Download the launcher installer
  • Open the downloaded .dmg file and drag the CCLauncher application to your Applications folder
  • Return to this page and launch the resource

In this activity, students explore what makes a "good fit" for a protein. They start with an exploration of the differences between small molecules and macromolecules such as proteins.  They use cartoon representations to build "protein complexes" in a model and test the effects of shape and temperature on the strength of the fit.  Students review polar and non-polar molecules and identify polar and non-polar regions of a given protein.  Finally, students are challenged to find the best fit for a particular receptor based on shape and charges.

» Teacher Guide

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WARNING: Your data will not be saved. To save data, run this activity as a registered user. You can register at the project portal. Please view the requirements below before launching this activity.

Copyright
© Copyright The Concord Consortium

Record Link
<a href="">The Concord Consortium. Protein Partnering and Function. Concord: The Concord Consortium, 2012, October 15.</a>

AIP
Protein Partnering and Function (The Concord Consortium, Concord, 2012, October 15), WWW Document, (https://concord.org/).

AJP
Protein Partnering and Function (The Concord Consortium, Concord, 2012, October 15), WWW Document, (https://concord.org/).

APA
Protein Partnering and Function. (2012, October 15). Retrieved 2017, February 20, from The Concord Consortium: https://concord.org/

Disclaimer: The Concord Consortium offers citation styles as a guide only. We cannot offer interpretations about citations as this is an automated procedure.

Requirements

This activity requires the Java Runtime Environment version 5 (sometimes referred to as 1.5) or later with Java Webstart. You can download it at java.com.

On OS X 10.9 or newer, you will need to install a launcher application to run this Java activity. If you have not already installed it, please:

  • Download the launcher installer
  • Open the downloaded .dmg file and drag the CCLauncher application to your Applications folder
  • Return to this page and launch the resource

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Science of Atoms and MoleculesThis resource is a part of the Concord Consortium's Science of Atoms and Molecules project.

Grade Level
High School
Subject
Biology, Chemistry
Focus Area
Modeling and Simulation
Rating
5
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